| |
Department of Surgical Oncology
The Department of Surgical Oncology at MIOT hospitals
was started in September 2008, and currently has 2
consultants. Major cancer operations are regularly
performed, including
|
 |
Head and Neck
cancer |
|
 |
Breast cancer |
|
 |
Thoracic cancer
operations |
|
 |
Liver,
Pancreatic and Gastro Intestinal cancer |
|
 |
Gynaecologic and
Colorectal cancer |
|
 |
Bone and Soft
tissue cancer |
|
|
More than 40
cases have been performed so far, with excellent
results.
The Department of Surgical Oncology is headed by Dr.
Ajit Pai, who trained in surgical oncology at the Tata
Memorial Hospital, Mumbai for 6 years. He obtained
further specialized training in surgery for liver,
biliary and pancreatic cancers at Tokyo, Nagoya and
Kyoto Universities, and in keyhole surgery for
esophageal cancer at Osaka university school of
medicine, Japan. He also completed a fellowship in
pancreatic cancer surgery at the University of
Heidelberg, Germany. His special interests are in
keyhole surgery for esophageal cancer and surgery for
liver, pancreatic and gastrointestinal cancers.
The Department Surgical Oncology is aided by an American
qualified pathologist and haematopathologist.
| |
 |
|
Dual Head Nuclear Scan |
|
Facilities
MIOT Hospitals is equipped with state-of-the-art
diagnostic support services like MRI and 64-slice CT
scanner with 3-Dimensional reconstruction abilities. It
gives exact information about cancer spread to various
adjacent organs and blood vessels. Interventional
radiology helps to block tumour blood supply and to give
chemotherapy inside the tumour. The Dual head GAMMA
camera in nuclear medicine detects even minute spread
like bone metastasis. Bone Tumour patients get the best
care as MIOT’s Orthopaedic Department is one the best in
the country.
MIOT has a
full fledged histopathology lab with
immuno-histochemistry and also frozen section facilities
which gives report |
in 20
minutes and guides the extent of surgery. Endoscopy,
colonoscopy, fibre-optic bronchoscopy are used to
identify exact location and extent of disease and during
follow-up. The availability of facilities for
Bronchoscopy and a Pulmonologist help the Oncology
Department to manage lung cancer well.
Advanced
gadgets like electro-surgical devices, Argon Plasma
Coagulator and a wide array of surgical staplers are
routinely used here.
High quality MRI Mammography is available for Breast
Cancer Management and prevention. The hospital also has
a Cytology Department to aid detection of Cervical
Cancer
We are planning to start the latest Radiation Oncology
Department inside the hospital premises so that all the
modalities of a cancer patient’s management will be
under one roof. This will be unique in the city of
Chennai.
Cancer -
Is it curable?
Cancer is curable if detected early. Early detection of
cancer is possible by screening, and this has led to
improved survival in cancers of the breast and cervix.
If a person has regular medical check up, and reports
immediately to the doctor if he has any of the warning
signs (unexplained weight loss, loss of appetite, lump
in the breast or bleeding from the nipple, recent change
of bowel habits, vaginal bleeding after menopause,
change in shape/size or bleeding from a mole, chronic
cough), then cancer may be detected at an earlier stage
and cure is possible in most cases.
Cancer detection programmes - Screening for cancer
Screening is detection of cancer at a very early stage,
by testing normal persons with simple, painless tests.
The aim of screening is to decrease the death rate from
a particular cancer. Screening programmes exist for
breast, colorectal (large intestine), cervix, lung and
prostate cancer.
Examples of screening tests are:
|
 |
Mammography -
for breast cancer |
|
 |
Pap Smear - for
cervix cancer |
|
 |
Colonoscopy -
for colon cancer |
|
 |
Blood tests - to
detect a substance called PSA in prostate cancer and |
|
 |
CT scan - for
lung cancer. |
|
MIOT has a Master Health Check up scheme, in which
ladies are screened for breast cancer with digital
mammography and MR mammography. The Gynaecology
department routinely screens all comers for cervix
cancer. Many of the early cancer cases treated by the
Oncology department are referred from the Master Health
check up department.
MIOT Hospitals - Ideally suited for care of cancer
patients
Apart from the highly trained Oncologist and
state-of-the-art facilities, MIOT has a large verdant
campus, with gardens and fountains. Patients are given
individual attention, and can recuperate well in the
quiet, beautiful surroundings. Patients are extensively
counselled before and after surgery, so that they have
no doubts or fears. Adequate time for patient-doctor
interaction and follow up visits are provided.
Cancer treatment at MIOT
Hospitals - Cases studies
Case
Study 1
- Cancer Type: Liver cancer
- Diagnosis:
| |
 |
|
CT scan of Liver |
|
|
 |
67 year old man |
|
 |
Abdominal pain
of 1 week duration |
|
 |
On examination,
good general condition, no jaundice |
|
 |
Liver was
enlarged |
|
 |
CT scan liver/
Liver function tests/Tumour markers[AFP]were done |
|
- Treatment:
TACE
He underwent
a procedure called Trans arterial chemo embolisation or
TACE, wherein the blood supply to the tumour is blocked
through a pinhole puncture in a thigh blood vessel,
along with injection of chemotherapy directly into the
tumour.
| |
 |
|
TACE of ruptured HCC |
|
|
|
 |
 |
|
Post Embolisation CT Scan |
|
- Surgery:
Three weeks after TACE, the patient underwent a
successful operation to remove the tumour bearing
portion of the liver. He is doing well, six months after
surgery.
(The surgery photos are very disturbing, kindly view
at your own risk.)
Case
Study 2
- Cancer Type: Parotid Tumour
- Diagnosis and treatment:
Young lady from abroad, presented with a large tumour
over the right side of the face and jaw, arising from
the parotid gland. She underwent a very major surgery to
remove the parotid gland, the skin of the cheek, part of
the jaw bone, and then plastic surgery using tissues
from her back to fill the defect so created.
(The surgery photos are very disturbing, kindly view
at your own risk.)
Case
Study 3
- Cancer Type: Thyroid cancer
- Diagnosis and treatment:
|
 |
40 year old man,
presented with a hard Thyroid swelling of 3 years duration |
|
 |
Needle biopsy
confirmed it was a Thyroid cancer, and he underwent complete
removal of the Thyroid gland, and post operative Radioiodine
treatment, and is doing well. |
|
(The surgery photos are very disturbing, kindly view
at your own risk.)
Case
Study 4
- Tumour Type: Esophageal cyst
- Diagnosis and treatment:
|
 |
24 year old lady
from sudan |
|
 |
Dysphagia since
1 year |
|
 |
CT scan showed a
posterior mediastinal mass |
|
 |
At surgery, a
cyst was removed from the esophageal wall |
|
(The surgery photos are very disturbing, kindly view
at your own risk.)
Department of Medical Oncology
|
 |
Dr.
Bellarmine
M.D., A.B., F.A.C.P
Consultant in Medical Oncology & Haematology |
The Department of Medical Oncology is headed by
Dr.Bellarmine who is an Emeritus Member of American
Society of Clinical Oncology. Dr.Bellarmine has 30 years
of experience as Medical Oncologist and 9 yrs of
professional experience as Professor in various
prestigious centres in Tamil Nadu, including SRMC. He
holds Medical Oncology fellowship from Hershey Medical
Centre, Pennsylvania State University, USA and Internal
Medicine Residency from West Virginia University, USA.
Here treatment for cancer is provided using Medicine –
a) Injection and b) Tablets. The treatment is given once
in 3 weeks and approximately for 6 months, depending
upon the nature of cancer and patients health condition.
All chemotherapy drugs are administered here. Side
effects: Nausea and Vomiting for 1 or 2 days. The
pioneering Department of Interventional Radiology is practised in the technique of infusing chemotherapy
drugs through the artery. Monoclonal Antibodies and
Thyrosine Kinase Inhibitors are available for the target
therapy of cancers.
Monoclonal antibody therapy: It is the use of
monoclonal antibodies (or mAb) to specifically target
cells. The main objective is stimulating the patient's
immune system to attack the malignant tumour cells and
the prevention of tumour growth by blocking specific
cell receptors.
We also provide a) pain management, b) colony
stimulating factors for improvement of WBC, haemoglobin
and platelets. Blood bank is available to assist
transfusion.
FAQ
1. What is cancer
2. Causes of cancer
3. Symptoms of cancer
4. Organs affected by cancer
5. Spread of cancer
6. Treatment of cancer
1. What is cancer?
Cancer is the name given to a group of diseases, which
have one feature in common: “uncontrolled growth of
cells”, which is of no use to the body. Normally
cell growth is balanced by death of equal numbers of
cells - a process called apoptosis or programmed cell
death. When this process is disrupted, a mass of cells
is produced - commonly known as a ‘tumour’.
Tumour:
Tumours may be benign or malignant:
|
 |
Benign: Here
tumour growth is slow and spread does not occur to other
parts of the body. |
|
 |
Malignant: A
malignant tumour on the other hand, can destroy organs
locally and spread to other parts of the body, such as
lungs, liver and bones-a unique ability, called metastasis. |
|
Cancers are
of different types, depending on the tissue from which
they arise: Broadly, 4 types are recognized;
|
 |
Carcinomas -
which arise from the layers that cover the body[skin] or
line the body-mucosa of nose, throat, lungs, food pipe,
stomach, intestine etc, |
|
 |
Sarcomas - which
arise from soft tissues such as muscle, fat, blood vessels
or from bones, |
|
 |
Leukaemia’s -
which arise from the bone marrow and spread into the blood
and |
|
 |
Lymphomas -
which originate from the lymphnodes and spleen. |
|
2. Causes of cancer
The cause of cancer is multifactorial - multiple agents
may act to produce cancer in a particular person. The
risk of developing cancer increases with age - 80% of
all cancers occur in those aged above 55 years. The
final common pathway is damage to the genetic component
of the cell (DNA), which leads to uncontrolled cell
growth.
The common causative factors may be:
|
 |
External: such
as dietary (high fat diet, alcohol), tobacco, excessive sun
exposure, viral infections like Hepatitis B, industrial
chemicals; or |
|
 |
Internal:
inherited defective genes (which explains how cancer ‘runs’
in some families), or |
|
 |
Reproductive
history (late age at first child birth for breast cancer) |
|
3. Symptoms of cancer
Cancer being a disease which affects any organ in the
body, the symptoms are varied, and there is no
particular symptom which can accurately predict the
presence of cancer. The exact symptoms depend on the
location of the cancer, which part of the organ is
affected, how fast the cancer is growing and whether it
has spread to other parts. Cancer occurring in outer
parts of the body, such as skin, breast, limbs,
testicles or nose and mouth, may present with a visible
swelling or ulcer, and may be diagnosed earlier.
There are certain warning signs of cancer, which should
be further investigated:
|
 |
Unexplained
weight loss |
|
 |
Loss of appetite |
|
 |
Lump in the
breast or bleeding from the nipple |
|
 |
Recent change of
bowel habits |
|
 |
Vaginal bleeding
after menopause |
|
 |
Change in
shape/size or bleeding from a mole |
|
 |
Chronic cough |
|
4. Organs
affected by cancer
Cancer can
affect every organ and cell type in the body, though
some organs such as the eye and heart are rarely
affected. Some of the common cancers are:
|
 |
Mouth and tongue
cancers |
|
 |
Throat and voice
box (larynx) cancers |
|
 |
Lung cancer |
|
 |
Esophageal and
stomach cancer |
|
 |
Liver cancer |
|
 |
Pancreatic
cancer |
|
 |
Colon and rectal
(Large intestine) cancer |
|
 |
Kidney and
bladder cancer |
|
 |
Prostate cancer |
|
 |
Ovarian, uterine
and cervix cancers |
|
 |
Breast cancer |
|
 |
Bone cancers |
|
 |
Blood cancer (Leukemias) |
|
5. Spread of cancer
The hall mark of cancer and what makes it a deadly
disease, is its ability to destroy surrounding organs
and spread [metastasize] to far away organs. Cancer
which has spread to a far away organ is called stage IV
cancer, and is generally not curable. It is treated with
medicines, called chemotherapy. The common organs to
which spread occurs are those with rich blood flow, like
lung, liver and bone. Each cancer has a preference for
certain organs; eg. Stomach cancer spreads to the liver,
bone cancer to the lungs.
Once cancer spreads, it causes the patient’s condition
to rapidly worsen - weakness sets in, appetite goes down
and respiratory or liver failure sets in. Survival after
metastases are found is usually less than a year.
6. Treatment of cancer
The aim of cancer treatment is to relieve symptoms, cure
the patient and prolong or save life. All these aims may
not be met in every case. When cancer is detected early,
treatment is very effective and patients are usually
cured.
In patients who present with advanced disease, complete
cure may not be possible, and treatment aims to control
the disease, improve quality of life and to keep the
patient normal and comfortable as long as possible. The
treatment of each patient is designed to suit an
individual and depends on the age of the patient,
general condition, type of cancer and stage of disease.
There may be only one treatment or combination of
treatments.
There are
five main modalities of treatment for cancer:
Surgery
Surgery is the most important part of the cancer
treatment. Surgery removes cancer cells from the body by
cutting away the tumour and any tissues surrounding it
which may contain cancer cells, including the lymphnodes.
It is a simple, safe and effective method when cancer is
small and confined to the site of origin. It is best
suited for certain cancers like breast cancer, head and
neck cancers, early cancers of the cervix and lung, many
skin cancers, soft tissue cancers and gastrointestinal,
liver and pancreatic cancers. Surgery may also be used
in advanced cases to relieve symptoms such as bleeding
and blockage of the food pipe, intestine or urinary
passage.
Radiotherapy
Radiotherapy is a form of treatment which uses
radiation, a special kind of energy carried by waves or
a stream of particles originating from radioactive
substances and delivered by special machines. These
radioactive x-rays or gamma rays can penetrate the cell
wall and damage the nucleus of the cell which prevents
growth and division of cells. This also affects the
normal cells but these cells recover more fully than
cancer cells. Radiotherapy is required in 50% to 70% of
patients, usually before surgery to shrink large tumours,
or after surgery to destroy cells left behind after
surgery at the site of tumour origin. Radiation is also
used in patients with metastases, to relieve pain,
bleeding or pressure symptoms; eg to relieve paralysis
caused by a tumour pressing on the spinal cord.
Modern radiotherapy is very safe, and is technology
driven. Recent advances include Intensity Modulated
Radiation Therapy [IMRT] which is the delivery of
radiation with high precision, so as to spare normal
tissues, and reduce side effects. Improvements in
radiotherapy equipment, technique and applications, have
led to an increasing role both in local treatment and
also in its use as a whole-body treatment, as part of
bone marrow transplantation techniques for leukaemia’s
and lymphomas.
Chemotherapy
Chemotherapy uses drugs which interfere with the growth
and division of malignant cells. Once the drugs are
administered, they circulate throughout the body. It is
advantageous over surgery & radiation for treating
cancer that is systemic (spread throughout the body).
Chemotherapy is the main modality for cancers like
leukemia (blood cancer), lymphomas, certain lung cancers
and paediatric cancers. Chemotherapy may be used before
surgery to shrink large tumours, and make surgery
easier, in breast, esophageal, rectal and bone cancers.
Chemotherapy is also used after surgery to treat cells
shed in the blood, so as to prevent reappearance of
tumours.
The side-effects of the chemotherapy include nausea,
vomiting, hair loss, diarrhoea, weakness etc. which are
temporary and completely reversible. Modern chemotherapy
is very safe and well tolerated and is often given on an
outpatient basis.
Hormonetherapy
Hormonetherapy has limited use in cancer treatment since
only minority of tumours are hormone sensitive e.g.
breast and prostate cancer. This therapy provides
systemic means of treatment, i.e. to the whole body, but
without the side effects of chemotherapy.
Immunotherapy
Immunotherapy is a form of treatment which stimulates
the body’s immune system to destroy cancer cells. It is
expensive, and useful only in a few tumours such as
melanomas (type of skin cancer) and renal cancers.