The basic requirement for successful kidney transplantation is a match of the blood groups. This restricts the number of donors available for a patient amongst his blood relatives. With a special technology, it is possible to remove this barrier and perform transplantation across blood groups. The leaders of this technology are from Tokyo Women Medical University, Japan and MIOT in collaboration with them has successfully  performed a transplant with the father having ‘B’ blood group donating the kidney to his son having ‘O’ blood group. The transplantation was performed 3 months back and both the patient and donor are doing well having normal kidney functions. Normally a person with ‘O’ blood group has anti ‘A’ and anti ‘B’ antibodies, which prevents person with ‘B’ or ‘A’ blood group to donate. The Japanese technology involves removal of antibodies